Lung cancer


Lung cancer trials open in South Yorkshire

LUN090
Lung ART Phase III study comparing post-operative conformal radiotherapy to no post-operative radiotherapy in patients with completely resected non-small cell lung cancer and mediastinal N2 involvement
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

LUN093
A Phase I/IIa study of the safety, tolerability and biological effect of single and repeat administration of the selectively replication-competent herpes simplex virus HSV1716 into the tumour-bearing pleural cavity (intrapleural) in patients with inoperable malignant pleural mesothelioma
Information from ClinicalTrials.gov about this trial

LUN103
PIN A randomised phase II trial of Olaparib maintenance versus placebo monotherapy in patients with chemosensitive advanced non-small cell lung cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

LUN104
MARS2 A study to determine if it is feasible to recruit into a randomised trial comparing extended pleurectomy decortication versus no extended pleurectomy decortication in the multimodality management of patients with malignant pleural mesothelioma
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

LUN105
SPLENDOUR ETOP 5-12/ EORTC 08111 (SPLENDOUR): A randomised, open-label phase III trial evaluating the addition of denosumab to standard first-line anticancer treatment in advanced NSCLC
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

LUN110
Lung HeXeRT Advanced proton, hyperpolarised 3-helium and 129-xenon magnetic resonance imaging for lung cancer radiotherapy planning and evaluation
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

LUN111
National Lung Matrix Trial Multi-drug, genetic marker-directed, non-comparative, multi-centre, multi-arm phase II trial in non-small cell lung cance
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

LUN112
CHECKMATE 171 An open-label, multicentre clinical trial with Nivolumab (BMS-936558) monotherapy in subjects with advanced or metastatic Squamous Cell (Sq) Non-Small Cell Lung Cancer (NSCLC) who have received at least one prior systemic regimens for the treatment of Stage IIIb/IV SqNSCLC
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

LUN113
PEARLS A randomised phase 3 trial with anti-PD-1 monoclonal antibody pembrolizumab (MK-3475) versus placebo for patients with early stage NSCLC after resection and completion of standard adjuvant therapy
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

LUN114
SOLAR - An open-label, randomised Phase 3 efficacy study of ASP8273 vs Erlotinib or Gefitinib in first-line treatment of patients with Stage IIIB/IV non-small cell lung cancer tumours with EGFR activating mutations
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

LUN115
CheckMate 451 – A randomised, multicentre, double-blind, Phase 3 study of Nivolumab, Nivolumab in combination with Ipilimumab, or placebo as maintenance therapy in subjects with Extensive-stage Disease Small Cell Lung Cancer (ED-SCLC) after completion of platinum-based first line chemotherapy
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

LUN118
Protocol I4D-MC-JTJH A Phase 2 Study of LY2606368 in Patients with Extensive Stage Disease Small Cell Lung Cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

MSS008
SarCaBon A randomised double-blind phase II trial of saracatinib versus placebo for cancer-induced bone pain
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

MSS012
Select-d: Anticoagulation therapy in selected cancer patients at risk of recurrence of venous thromboembolism
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

MSS015
SPIRE SGI-110 to potentiate platinum response: a phase Ib/IIa open label clinical trial combining SGI-110 with cisplatin and gemcitabine chemotherapy
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

XXX154
GEM Genetics of EGFR Mutation Study (GEM): a translational study of the EORTC lung group
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

XXX163
SMP2 CRUK Stratified Medicine Programme Two
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

XXX172
DIAPHRAGM - Diagnostic and Prognostic biomarkers in the Rational Assessment of Mesothelioma
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.