Gastro-intestinal cancer


Gastro-intestinal cancer trials open in South Yorkshire - includes upper GI, and colorectal trials

Upper GI trials

GIT055
ST03: A randomised phase II/III trial of peri-operative chemotherapy with or without bevacizumab in operable adenocarcinoma of the stomach and gastro-oesophageal junction
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT059
ESPAC - 4 European Study Group for Pancreatic Cancer (ESPAC) - Trial 4. Combination versus single agent adjuvant chemotherapy in resectable pancreatic cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT090
GO2 Alternate chemotherapy for frail or elderly patients with advanced gastric or oesophageal cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT092
ABC-06 A phase 3 randomised multi-centre open-label study of active symptom control (ASC) alone or ASC with oxaliplatin/ 5-FU chemotherapy for patients with locally advanced/ metastatic biliary tract cancers previously treated with cisplatin/ gemcitabine chemotherapy
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT096 (STH18384)
ESPAC-5F: European study group for pancreatic cancer - TRIAL 5F Four arm, prospective, multicentre, randomised feasibility trial of immediate surgery compared with neoadjuvant chemotherapies and neoadjuvant chemoradiotherapy.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT100
NCRN - 3137: STOP-HCC TheraSphere in Unresectable Hepatocellular Carcinoma (HCC) TS103
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

GIT101
PLATFORM Planning Treatment for Oesophago-Gastric Cancer: a Randomised Maintenance Therapy Trial
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT102
BALLAD A trial to evaluate the potential benefit of adjuvant chemotherapy for small bowel adenocarcinoma
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

GIT104
ROCS Study Palliative radiotherapy in addition to self-expanding metal stent for improving outcomes of dysphagia and survival in advanced oesophageal cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT105
ACELARATE A phase III, open-label, multicentre randomised clinical study comparing Acelarin (NUC-1031) with Gemcitabine in patients with metastatic pancreatic carcinoma
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT106
ACTICCA-1 - adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

GIT111
SCOPE 2 A randomised phase II/III trial to study radiotherapy dose escalation in patients with oesophageal cancer treated with definitive chemo-radiation with an embedded phase II trial for patients with a poor early response using positron emission tomography (PET)
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

GIT112 (open in Doncaster)
HART Hughes Abdominal Repair Trial - abdominal wall closure techniques to reduce incidence of incisional hernias: multicentre pragmatic randomised trial
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

Colorectal trials

GIT054
FOxTROT Fluoropyrimidine, oxaliplatin and targeted receptor pre-operative therapy: a controlled trial in high-risk operable colon cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT073
PulMiCC A randomised trial of Pulmonary Metastasectomy in Colorectal Cancer
The PulMiCC website
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT074
ARISTOTLE A phase 3 trial comparing standard versus novel CRT as pre-operative treatment for MRI defined locally advanced rectal cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT091
FOCUS 4 Molecular selection of therapy in colorectal cancer : a molecularly-stratified randomised controlled trials programme
Focus 4 study website
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT097
InterAACT An International Multicentre Open Label Randomised Phase II Advanced Anal Cancer Trial Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxel in Patients With Inoperable Locally Recurrent or Metastatic Disease
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

GIT098
EPOCH Protocol TS-102: A phase 3 clinical trial evaluating Therasphere in patients with metastatic colorectal carcinoma of the liver who have failed first line chemotherapy
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

GIT113
COTEZO COBIMETINIB GO30182 Study A Phase III, open-label, multicenter, three-arm, randomized study to investigate the efficacy and safety of cobimetinib plus atezolizumab and atezolizumab monotherapy vs. regorafenib in patients with previously treated unresectable locally advanced or metastatic colorectal adenocarcinoma
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)


All sites

MSS012
Select-d: Anticoagulation therapy in selected cancer patients at risk of recurrence of venous thromboembolism
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

MSS013
Add Aspirin - A phase III double-blind placebo-controlled randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

MSS015
SPIRE SGI-110 to potentiate platinum response: a phase Ib/IIa open label clinical trial combining SGI-110 with cisplatin and gemcitabine chemotherapy
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)