Breast cancer



Breast cancer trials open in South Yorkshire


BRE140
FAST-Forward Randomised clinical trial testing a 1-week course of curative whole breast radiotherapy against a standard 3-week schedule in terms of local cancer control and late adverse effects in patients with early breast cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

BRE151
STAKT The short term effects of an AKT inhibitor (AZD5363) on biomarkers of the AKT pathway and anti-tumour activity in a breast cancer paired biopsy study
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE153
MANTA A randomised Phase II study of Fulvestrant in combination with the dual mTOR inhibitor AZD2014 or Everolimus or Fulvestrant alone in Estrogen receptor-positive advanced or metastatic breast cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE155
Optimal Personalised Treatment of early breast cancer using Multiparameter Analysis (OPTIMA)
(On hold for recruitment)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE157
POSNOC Positive sentinel node: adjuvant therapy alone versus adjuvant therapy plus clearance or axillary radiotherapy. A randomised controlled trial of axillary treatment in women with early stage breast cancer who have metastases in one or two sentinel nodes
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE158
LORIS - A Phase III Trial of Surgery versus Active Monitoring for Low Risk Ductal Carcinoma in Situ (DCIS)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE160
OLYMPIA – A randomised, double-blind, parallel group, placebo-controlled multicentre Phase III study to assess the efficacy and safety of olaparib versus placebo as adjuvant treatment in patients with germline BRCA1/2 mutations and high risk HER2 negative primary breast cancer who have completed definitive local treatment and neoadjuvant or adjuvant chemotherapy
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE161
MAMMO-50 Mammographic surveillance in breast cancer patients aged 50 years and over: a randomised controlled trial
MAMMO-50 study website
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE162
UNIRAD Randomised, double-blind, multicentre Phase III trial evaluating the safety and benefit of adding Everolimus to adjuvant hormone therapy in women with poor prognosis, ER+ and HER2- primary breast cancer who remain free of disease after at least 1 year of adjuvant hormone therapy
Information from ClinicalTrial.gov website about this trial (includes main eligibility criteria & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

BRE163
A phase II randomized, double-blind, placebo-controlled trial of radium-223 dichloride versus placebo when administered to metastatic HER2 negative hormone receptor positive breast cancer with bone metastases treated with hormonal treatment background therapy
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE165
CiPHER – Phase II multicentre study assessing the efficacy of Cabazitaxel in patients with HER2-negative metastatic breast cancer and having unresectable brain metastases
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

BRE166
CARBON A randomised phase IB/IIA study of capecitabine plus radium-223 (Xofigo™) in metastatic breast cancer patients with bone metastases

BRE167
ROSCO – Response to Optimal Selection of neo-adjuvant Chemotherapy in Operable breast cancer: A randomised Phase III stratified biomarker trial of neo-adjuvant 5-Fluorouracil, Epirubicin and Cyclophosphamide vs Docetaxel and Cyclophosphamide chemotherapy
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

BRE169
IBIS 3 – An international Breast Intervention Study investigating Prevention of Late Recurrence in ER+ breast cancer survivors following 5 years of adjuvant treatment
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

BRE171
IMPassion 130 – A Phase III, multicentre, randomised, placebo-controlled study of Atezolizumab (anti-PD-L1 antibody) in combination with nab-Paclitaxel compared with placebo with nab-Paclitaxel for patients with previously untreated metastatic triple-negative breast cancer
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

MSS008
SarCaBon A randomised double-blind phase II trial of saracatinib versus placebo for cancer-induced bone pain
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

MSS012
Select-d: Anticoagulation therapy in selected cancer patients at risk of recurrence of venous thromboembolism
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

MSS013
Add Aspirin - A phase III double-blind placebo-controlled randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.

MSS015
SPIRE SGI-110 to potentiate platinum response: a phase Ib/IIa open label clinical trial combining SGI-110 with cisplatin and gemcitabine chemotherapy
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.
Information from UK Clinical Trials Gateway website about this trial (includes main eligibility criteria, accrual & contact information)

XXX077
Identification and molecular analyses of families with susceptibility to breast and/or ovarian cancer (formerly 'Identification and molecular analyses of families with susceptibility to breast cancer')

XXX079
DETECT Development of Biomarkers to improve outcomes for breast cancer patients with or at risk of bone metastases
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.


XXX099
The role of angiogenesis and genome stability in breast cancer

XXX133
Bridging the Age Gap in Breast Cancer: Improving Outcomes for Older Women
Information from CancerHelp UK website about this trial. CancerHelp UK is a free information service about cancer and cancer care for people with cancer and their families.